Journal: Diagnostics

Article Title: An Antibody-Aptamer-Hybrid Lateral Flow Assay for Detection of CXCL9 in Antibody-Mediated Rejection after Kidney Transplantation

doi: 10.3390/diagnostics12020308

Figure Lengend Snippet: Schematic of the basic structure of the developed aptamer-antibody-hybrid-lateral flow assay (hybrid-LFA) with sample pad, nitrocellulose membrane and absorbent pad, providing the necessary lateral flow fluids and overlapping glued to a backing card. The hybrid-LFA uses a capture antibody in the test zone (TZ) and a detection aptamer conjugated to gold nanoparticles both with high affinity for CXCL9. ( A ) test platform composition, ( B ) positive test (two red lines, TZ and CZ), ( C ) negative test (one red line, CZ) (modified according to Seiler et al. ).

Article Snippet: Gold nanoparticles (AuNP) were kindly provided by Fassisi GmbH (Goettingen, Germany).

Techniques: Lateral Flow Assay, Membrane, Modification

Journal: Journal of Drug Delivery Science and Technology

Article Title: Nanotherapeutics for treating coronavirus diseases

doi: 10.1016/j.jddst.2021.102634

Figure Lengend Snippet: Schematic illustrating the dendritic cell targeting chitosan nanoparticles.

Article Snippet: Gold nanoparticles (AuNPs) were obtained as a commercial gold colloid and coated with Bis( p -sulfonatophenyl)phenylphosphine dihydrate dipotassium salt (BSSP).

Techniques:

Journal: Journal of Drug Delivery Science and Technology

Article Title: Nanotherapeutics for treating coronavirus diseases

doi: 10.1016/j.jddst.2021.102634

Figure Lengend Snippet: Schematic illustrating the immunization of BALB/c mice with saRNA encoding pre-fusion stabilized S protein encapsulated in lipid nanoparticles.

Article Snippet: Gold nanoparticles (AuNPs) were obtained as a commercial gold colloid and coated with Bis( p -sulfonatophenyl)phenylphosphine dihydrate dipotassium salt (BSSP).

Techniques:

Journal: Journal of Drug Delivery Science and Technology

Article Title: Nanotherapeutics for treating coronavirus diseases

doi: 10.1016/j.jddst.2021.102634

Figure Lengend Snippet: Schematic illustrating the diphyllin-encapsulated PEG-PLGA nanoparticles.

Article Snippet: Gold nanoparticles (AuNPs) were obtained as a commercial gold colloid and coated with Bis( p -sulfonatophenyl)phenylphosphine dihydrate dipotassium salt (BSSP).

Techniques:

Journal: Journal of Drug Delivery Science and Technology

Article Title: Nanotherapeutics for treating coronavirus diseases

doi: 10.1016/j.jddst.2021.102634

Figure Lengend Snippet: Types of nanotechnology-based therapeutics used in different types of coronavirus infections, their synthesis methods, the purpose of use, and the outcome.

Article Snippet: Gold nanoparticles (AuNPs) were obtained as a commercial gold colloid and coated with Bis( p -sulfonatophenyl)phenylphosphine dihydrate dipotassium salt (BSSP).

Techniques: Virus, Double Emulsion, Adjuvant, Encapsulation, Recombinant, Vaccines, Affinity Chromatography, Activation Assay, Expressing, Gene Expression, Purification, Incubation, Conjugation Assay, Synthesized, Centrifugation, Plasmid Preparation, Modification, Concentration Assay, Neutralization, Infection, Produced, Sequencing, Activity Assay, Binding Assay, Solvent, Evaporation, Inhibition

Journal: Frontiers in Bioengineering and Biotechnology

Article Title: Nano-Technological Approaches for Targeting Kidney Diseases With Focus on Diabetic Nephropathy: Recent Progress, and Future Perspectives

doi: 10.3389/fbioe.2022.870049

Figure Lengend Snippet: Schematic mechanism of kidney targeted drug delivery. The renal artery transports drug-carrying nanoparticles to the afferent arteriole, where they remain in the bloodstream or are filtered out of the blood by the kidneys in the glomerular capillaries for further processing. Renal components such as the endothelial cells, GBM, and glycocalyx can all be modified to assist in the selection of NPs for filtration. Following filtering, NPs can interact with podocytes in the Bowman’s lumen. The NPs are transported to the proximal tubule, where they interact with proximal epithelial cells and may be reabsorbed .

Article Snippet: Mesoscale NPs (MNPs) (up to 400 nm) were observed in proximal tubular cells, apparently delivered there through endocytosis as their size is larger than fenestrations. synthesized and investigated the effect of pomegranate peel extract-stabilized gold nanoparticles (PPE-AuNPs) on the mice with the streptozotocin-induced DN model.

Techniques: Modification, Selection, Filtration

Journal: Frontiers in Bioengineering and Biotechnology

Article Title: Nano-Technological Approaches for Targeting Kidney Diseases With Focus on Diabetic Nephropathy: Recent Progress, and Future Perspectives

doi: 10.3389/fbioe.2022.870049

Figure Lengend Snippet: Nano-technological for targeting renal diseases and DN.

Article Snippet: Mesoscale NPs (MNPs) (up to 400 nm) were observed in proximal tubular cells, apparently delivered there through endocytosis as their size is larger than fenestrations. synthesized and investigated the effect of pomegranate peel extract-stabilized gold nanoparticles (PPE-AuNPs) on the mice with the streptozotocin-induced DN model.

Techniques: Polymer, Ligand Binding Assay, Modification, Encapsulation